Publications

 

 

2020. CC Foster, RA Davis, SH Hausner, JL Sutcliffe. αvβ6-Targeted Molecular PET/CT Imaging of the Lungs After SARS-CoV-2 Infection. Journal of Nuclear Medicine, accepted. link

2020. SH Hausner, N Bauer, RA Davis, T Ganguly, SYC Tang, JL Sutcliffe. The effects of an albumin binding moiety on the targeting and pharmacokinetics of an integrin αvβ6-selective peptide labeled with aluminum [18F]fluoride. Molecular Imaging and Biology, accepted. link

2020. T Ganguly, SY Tang, N Bauer, JL Sutcliffe. Evaluation of Two Optical Probes for Imaging the Integrin αvβ6 − In Vitro and In Vivo in Tumor-Bearing Mice. Molecular Imaging and Biology, 22(5), 1170-1181. link

2019. RA Davis, SH Hausner, JL Sutcliffe. Peptides as Radiopharmaceutical Vectors. In: Lewis J., Windhorst A., Zeglis B. (eds) Radiopharmaceutical Chemistry. Springer

2019. RA Davis, C Drake, RC Ippish, M Moore, JL Sutcliffe. Fully automated peptide radiolabeling from [18F]fluoride. RSC Advances, 9, 8638. link 

2019. SYC Tang, RA Davis, T Ganguly, JL Sutcliffe. Identification, characterization, and optimization of integrin αvβ6-targeting peptides from a one-bead one-compound (OBOC) library: Towards the development of positron emission tomography (PET) Imaging Agents. Molecules, 24(2), 309. link 

2019. SH Hausner, RJ Bold, LY Cheuy, HK Chew, ME Daly, RA Davis, CC Foster, EJ Kim, JL Sutcliffe. Preclinical development and first-in-human imaging of the integrin αvβ6 with [18F]αvβ6-Binding Peptide in metastatic carcinoma. Clinical Cancer Research, 25(4), 1206. link

2018. JB White, LY Hu, DL Boucher, JL Sutcliffe. ImmunoPET imaging of alpha(v)beta(6) expression using an engineered anti-alpha(v)beta(6) Cys-diabody site-specifically radiolabeled with Cu-64: Considerations for optimal imaging with antibody fragments. Molecular Imaging and Biology, 20(1), 103-113. link

2017. OA Aboud, SL Habib, JF Trott, B Stewart, S Liang, AJ Chaudhari, JL Sutcliffe, RH Weiss. Glutamine addiction in kidney cancer suppresses oxidative stress and can be exploited for real-time imaging. Cancer Research, . link

2017. RA Davis, D Rippner, SH Hausner, SJ Parikh, AJ McElrone, JL Sutcliffe. In vivo tracking of copper-64 radiolabeled nanoparticles in lactuca sativa. Environmental Science & Technology, 51(21), 12537-12546. link

2017. LY Hu, KA Kelly, JL Sutcliffe. High-throughput approaches to the development of molecular imaging agents. Molecular Imaging and Biology, 19(2), 163-182. link

2016. RA Davis, K Lau, SH Hausner, JL Sutcliffe. Solid-phase synthesis and fluorine-18 radiolabeling of cycloRGDyK. Organic and Biomolecular Chemistry,14, 8659-63. link

2015. JB White, DL Boucher, KA Zettlitz, AM Wu, JL Sutcliffe. Development and characterization of an alpha(v)beta(6)-specific diabody and a disulfide-stabilized alpha(v)beta(6)-specific cys-diabody. Nuclear Medicine and Biology, 42(12), 945-57. link

2015. SH Hausner, N Bauer, LY Hu, LM Knight, JL Sutcliffe. The effect of bi-terminal PEGylation of an integrin alpha(v)beta(6)-targeted 18F-peptide on pharmacokinetics and tumor uptake. Journal of Nuclear Medicine, 56(5), 784-90. link

2015. DE Olberg, SH Hausner, N Bauer, J Klaveness, B Indrevoll, FO Levy, KW Andressen, M Dahl, JL Sutcliffe, I Haraldsen. Radiosynthesis of high affinity fluorine-18 labeled GnRH peptide analogues: in vitro studies and in vivo assessment of brain uptake in rats. Medicinal Chemistry Communications, 6, 708-14. link

2014. RC Cumming, DE Olberg, JL Sutcliffe. Rapid 18F-radiolabeling of peptides from [18F]fluoride using a single microfluidics device. RSC Advances, 4, 49529-34. link

2014. D Satpati, N Bauer, SH Hausner, JL Sutcliffe. Synthesis of [64Cu]DOTA-ADIBON3-Ala-PEG28-A20FMDV2 via copper-free click chemistry for PET imaging of integrin alpha(v)beta(6). Journal of Radioanalytical and Nuclear Chemistry, 302(2), 765-71. link

2014. LY Hu, N Bauer, LM Knight, Z Li, S Liu, CJ Anderson, PS Conti, JL Sutcliffe. Characterization and evaluation of 64Cu labeled A20FMDV2 conjugates for imaging the integrin alpha(v)beta(6). Molecular Imaging and Biology, 16(4), 567-77. link

2014. D Satpati, SH Hausner, N Bauer, JL Sutcliffe. Cerenkov luminescence imaging of alpha(v)beta(6) integrin expressing tumors using 90Y-labeled peptides. Journal of Labelled Compounds and Radiopharmaceuticals, 57(9), 558-65. link

2014. D Shin, J You, A Rahimian, T Vu, C Siltanen, A Ehsanipour, G Stybayeva, J Sutcliffe, A Revzin. Photodegradable hydrogels for capture, detection, and release of live cells. Angewandte Chemie International Edition, 53(31), 8221-4. link

2014. CM Griessinger, R Kehlbach, D Bukala, S Wiehr, R Bantleon, F Cay, A Schmid, H Braumüller, B Fehrenbacher, M Schaller, M Eichner, JL Sutcliffe, W Ehrlichmann, O Eibl, G Reischl, SR Cherry, M Röcken, BJ Pichler, M Kneilling. In vivo tracking of Th1 cells by PET reveals quantitative and temporal distribution and specific homing in lymphatic tissue. Journal of Nuclear Medicine, 55(2), 301-7. link

2014. DE Olberg, KW Andressen, FO Levy, J Klaveness, I Haraldsen, JL Sutcliffe. Synthesis and in vitro evaluation of small-molecule [F-18] labeled gonadotropin-releasing hormone (GnRH) receptor antagonists as potential PET imaging agents for GnRH receptor expression. Bioorganic and Medicinal Chemistry Letters, 24(7), 1846-50. link

2014. SH Hausner, N Bauer, JL Sutcliffe. In vitro and in vivo evaluation of the effects of aluminum [18F]fluoride radiolabeling on an integrin alpha(v)beta(6)-specific peptide. Nuclear Medicine and Biology, 41(1), 43-50. link

2013. SH Hausner, RD Carpenter, N Bauer, JL Sutcliffe. Evaluation of an integrin alpha(v)beta(6)-specific peptide labeled with [18F]fluorine by copper-free, strain-promoted click chemistry. Nuclear Medicine and Biology, 40(2), 233-9. link

2013. C Siltanen, D Shin, J Sutcliffe, A Revzin. Micropatterned photodegradable hydrogels for the sorting of microbeads and cells. Angewandte Chemie International Edition, 52(35), 9224–8. link

2012. JB White, SH Hausner, RD Carpenter, JL Sutcliffe. Optimization of the solid-phase synthesis of [18F]radiolabeled peptides for positron emission tomography. Applied Radiation and Isotopes, 70(12), 2720-9. link

2011. HR Davison, S Taylor, C Drake, PW Phuan, N Derichs, C Yao, EF Jones, JL Sutcliffe, AS Verkman, MJ Kurth. Functional fluorescently labeled bithiazole ΔF508-CFTR corrector imaged in whole body slices in mice. Bioconjugate Chemistry, 22 (12), 2593–9. link

2011. RD Carpenter, SH Hausner, JL Sutcliffe. Copper-free click for PET: Rapid 1,3-dipolar cycloadditions with a fluorine-18 cyclooctyne. ACS Medicinal Chemistry Letters, 2 (12), 885–9. link

2011. D Shin, JH Seo, JL Sutcliffe, A Revzin. Photolabile micropatterned surfaces for cell capture and release. Chemical Communications, 47, 11942-4. link

2009. MKJ Gagnon, SH Hausner, J Marik, CK Abbey, JF Marshall, JL Sutcliffe. High-throughput in vivo screening of targeted molecular imaging agents. Proceedings of the National Academy of Sciences, 106(42), 17904-9. link

2009. SH Hausner, CK Abbey, RJ Bold, MK Gagnon, J Marik, JF Marshall, CE Stanecki, JL Sutcliffe. Targeted in vivo imaging of integrin alpha(v)beta(6) with an improved radiotracer and its relevance in a pancreatic tumor model. Cancer Research, 69(14) 5843-50. link

2009. SH Hausner, DL Kukis, MKJ Gagnon, CE Stanecki, R Ferdani, JF Marshall, CJ Anderson, JL Sutcliffe. Evaluation of [64Cu]Cu-DOTA and [64Cu]Cu-CB-TE2A chelators for targeted PET imaging with an alpha(v)beta(6)-specific peptide. Molecular Imaging, 8(2), 111-21. link

2009. SJ DeNardo, R Liu, H Albrecht, A Natarajan, JL Sutcliffe, C Anderson, L Peng, R Ferdani, SR Cherry, KS Lam. 111In-LLP2A-DOTA polyethylene glycol–targeting alpha(4)beta(1) integrin: comparative pharmacokinetics for imaging and therapy of lymphoid malignancies. Journal of Nuclear Medicine, 50, 625-34. link

2009. RH Kim, JM Coates, TL Bowles, GP McNerney, J Sutcliffe, JU Jung, R Gandour-Edwards, FYS Chuang, RJ Bold, HJ Kung. Arginine deiminase as a novel therapy for prostate cancer induces autophagy and caspase-independent apoptosis. Cancer Research, 69 (2), 700-8. link

2009. SM Martin, RT O’Donnell,DL Kukis, C Abbey,  H McKnight, JL Sutcliffe, JM Tuscano (joint senior author). Imaging and pharmacokinetics of [64Cu]-DOTA-HB22.7 administered by intravenous, intraperitoneal, or subcutaneous injection to mice bearing non-Hodgkin’s lymphoma xenografts. Molecular Imaging and Biology, 11(2), 79-87. link

2008. SH Hausner, J Marik, MKJ Gagnon, JL Sutcliffe. In vivo positron emission tomography (PET) imaging with an alpha(v)beta(6) specific peptide radiolabeled using 18F-“click” chemistry: evaluation and comparison with the corresponding 4-[18F]fluorobenzoyl- and 2-[18F]fluoropropionyl-peptides. Journal of Medicinal Chemistry, 51(19), 5901-4. link

2008. J Huang , CCI Lee, JL Sutcliffe, SR Cherry, AF Tarantal. Radiolabeling rhesus monkey CD34+ hematopoietic and mesenchymal stem cells with [64Cu]-pyruvaldehyde-bis(N4-methylthiosemicarbazone) for microPET imaging. Molecular Imaging, 7(1), 1-11. link

2008. CM Parsons, JL Sutcliffe, RJ Bold. Preoperative evaluation of pancreatic adenocarcinoma. Journal of Hepato-Biliary Pancreatic Surgery, 15, 429-35. link

2008. H Zhang, J Kusunose, A Kheirolomoom, JW Seo, JY Qi, KD Watson, HA Lindfors, E Ruoslahti, JL Sutcliffe, KW Ferrara. Dynamic imaging of arginine-rich heart-targeted vehicles in a mouse model. Biomaterials, 29(12), 1976-88. link

2007. OH Aina, RW Liu, JL Sutcliffe, J Marik, CX Pan, KS Lam. From combinatorial chemistry to cancer-targeting peptides. Molecular Pharmaceuticals, 4(5), 631-51. link

2007. SH Hausner, D DiCara, J Marik, JF Marshall, JL Sutcliffe. Use of a peptide derived from foot-and-mouth-disease-virus (FMDV) for the non-invasive imaging of human cancer: Generation and evaluation of [18F]FBA-A20FMDV2 for in vivo imaging of integrin alpha(v)beta(6) expression with Positron Emission Tomography. Cancer Research, 67(16), 7833-40. link

2007. D DiCara, C Rapisarda, JL Sutcliffe, SM Violette, PH Weinreb, IR Hart, MJ Howard, JF Marshall. Structure-function analysis of Arg-Gly-Asp helix motifs in alpha(v)beta(6) integrin ligands. Journal of Biological Chemistry, 282(13), 9657-65. link

2007. J Marik, MS Tartis, H Zhang, JY Fung, A Kheirolomoom, JL Sutcliffe, KW Ferrara. Long-circulating liposomes radiolabeled with [18F]fluorodipalmitin ([18F]FDP). Nuclear Medicine and Biology, 34(2), 165-71. link

2007. J Marik, JL Sutcliffe. Fully automated preparation of n.c.a. 4-[18F]fluorobenzoic acid and N-succinimidyl 4-[18F]fluorobenzoate using Siemens CTI/CPCU chemistry module. Applied Radiation and Isotopes, 65, 199-203. link

2006. J Marik, J L Sutcliffe. Click for PET: Rapid preparation of [18F]fluoropeptides using Cu(I) catalyzed 1,3-dipolar cycloaddition. Tetrahedron Letters, 47, 6681-4. link

2006. J Marik, SH Hausner, LA Fix, MK Gagnon, JL Sutcliffe. Solid phase synthesis of 2-[18F]fluoropropionyl peptides. Bioconjugate Chemistry, 17, 1017-21. link

2002. JL Sutcliffe-Goulden, MJ O’Doherty, PK Marsden, IR Hart, JF Marshall, SS Bansal. Rapid solid phase synthesis and biodistribution of 18F-labelled linear peptides. European Journal of Nuclear Medicine and Molecular Imaging, 29(6), 754-9. link

2000. JL Sutcliffe-Goulden, MJ O’Doherty, SS Bansal. Solid phase synthesis of [18F]labelled peptides for positron emission tomography. Bioorganic and Medicinal Chemistry Letters, 10(14), 1501-3. link

 

   

 

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